Erythema nodosum
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It ferskynt as in pynlike erythematous nodule op 'e skonk.
References
Erythema nodosum is it meast foarkommende type panniculitis, karakterisearre troch pynlike reade nodules, benammen fûn op 'e legere skonken. De krekte oarsaak dêrfan bliuwt ûnbekend, mar it liket it resultaat fan in oerdreaune reaksje op ferskate triggers. Hoewol de oarsprong faaks ûnwis is, is it essensjeel om oare ûnderlizzende betingsten út te sluten foardat jo primary erythema nodosum diagnostisearje. It kin oanjaan op it begjin fan systemyske sykten lykas ynfeksjes, ûntstekking, kanker, of reaksjes op medisinen. Algemiene triggers omfetsje strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis ferwiist nei in ferskaat set fan inflammatoire omstannichheden dy't it fetweefsel ûnder de hûd beynfloedzje. Dizze betingsten binne ûngewoan by bern. Panniculitis kin it haadprobleem wêze yn in systemyske tastân as in reaksje sekundêr foar faktoaren lykas ynfeksje, blessuere of bepaalde medisinen. Nettsjinsteande de oarsaak litte de measte soarten panniculitis ferlykbere symptomen sjen, ynklusyf pynlike, reade nodules ûnder de hûd.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , in ûntstekking fan 'e fetlaach ûnder 'e hûd, is in seldsume tastân dy't meastentiids ferskynt as swollen knobbels of flekken. Erythema nodosum (EN) is it meast foarkommende type, faaks trigger troch ferskate faktoaren. Wylst sawat 55% fan 'e gefallen gjin dúdlike oarsaak hawwe, omfetsje mienskiplike triggers ynfeksjes, medisinen, bepaalde sykten lykas sarkoïdose en inflammatoare darmsykte, swangerskip en kanker. EN komt normaal foar by teens en jonge folwoeksenen, faker by froulju. It wurdt faak foarôfgien troch in algemien gefoel fan sykte dy't ien oant trije wiken duorret, mei symptomen lykas koarts en problemen mei boppeste luchtwegen. Dan ferskine reade nodules, meastentiids oan 'e bûtenkant fan' e earms en skonken, wêrtroch pine. De krekte oarsaak fan EN is net folslein begrepen, mar it wurdt leaud dat it ymmúnkompleksen belûke yn lytse bloedfetten fan 'e fetlaach, wat liedt ta ûntstekking. Typysk toant in biopsie ûntstekking yn 'e fetlaach sûnder skea oan bloedfetten. Sels sûnder spesifike behanneling foar de ûnderlizzende oarsaak lost EN faak op har eigen. Dat, de measte pasjinten hawwe allinich stypjende soarch nedich foar har symptomen.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Erythema nodosum wurdt klinysk diagnostearre. In biopsie kin wurde nommen en mikroskopysk ûndersocht om in ûnwisse diagnoaze te befestigjen. Om longsykten út te sluten, benammen sarkoïdose en tuberkuloaze, moat in röntgenfoto fan 'e boarst útfierd wurde.